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Additionally, myelination provides extrinsic trophic signals, which influence the normal maturation, maintenance, and long-term survival of axons (White et al., 2009

The unresolved question is whether excessive exposure, prolonged use, background food fortification, paternal and maternal methyl-donor status, or individual genetic susceptibility may produce unintended epigenetic effects in a subset of children

This paper details that the female KO mice had a pronounced reduction in GSTP1 compared to the male KO mice

Marques, E., Kramer, R

This dosage range derives from extrapolation of effective animal doses using standard interspecies scaling factors