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Pfizer also said that the placebo-adjusted reduction in mean body weight had ranged from -5% to -9.5% at 26 weeks and -8% to -13% at 32 weeks

doi: 10.1053/j.gastro.2016.10.012 137 GuntherCNeumannHNeurathMFBeckerC

The prevalence of pruritus varies depending on the underlying cause, with reports indicating rates of up to 70% in primary biliary cholangitis, 2.530% in chronic hepatitis C virus-related liver disease, and roughly 8% in cirrhosis attributed to hepatitis B virus infection (20)

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(5) More specifically, researchers comment that when the peptide was selected for further pharmacokinetic evaluation, where it was found to be present in plasma beyond 72 h