McMillin M, Frampton G, Thompson M et al
GSH levels have not only been found to be low in these patients, but replacement with N-acetylcysteine (NAC), a synthetic precursor for GSH, have been found to reduce thrombin activation and platelet activation [24]
While data on the association is still limited and experts dont believe these findings should be reason for concern for most patients, neuro-ophthalmologist Mary Labowsky, MD, assistant professor of ophthalmology at the University of Colorado School of Medicine, says it can be helpful to discuss with an eye doctor to assess the risk of developing NAION
Also, several regulatory molecules may influence its secretion
N-acetylcysteine and intestinal health: a focus on its mechanism of action
If dual therapy is being considered, it should only occur under close physician supervision with regular blood pressure and heart rate monitoring