For those considering AOD-9604 , realistic expectations remain essential
B12 Deficiency, Joint Pain, and Inflammation: What You Need to Know Severe joint pain directly stemming from B12 deficiency is rare
The preclinical evidence is encouraging
Weight fluctuates daily due to water retention, food volume, and hormonal cycles, so weekly averages provide better data than daily numbers
Anyone with kidney disease or suspected B12 deficiency or malabsorption should talk to their doctor about an appropriate B12 regimen
Prioritize protein (0.7 to 1.0 grams per pound of target body weight), eat frequent small meals rather than large infrequent ones, limit high-fat foods during dose increases to reduce nausea, stay hydrated, and avoid alcohol (which worsens both GI side effects and calorie intake)