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It would not be feasible to remove these from the diet altogether, such as glycerol 274 , amino acids that lead to acetate production through proteolytic fermentation by gut bacteria 275 , or by the degradation of mucins and other glycoproteins that are secreted by the gut lining 276

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In this sense, MOTS-c works as an endogenous exercise mimetic, triggering AMPK activation through the same molecular lever that exercise pulls, just from the inside [1]