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Early studies suggest that this new mechanism is effective in lowering uric acid levels.17 Arhalofenate: This medication both lowers uric acid and decreases inflammation in gout, and is being studied as a medication that might allow urate to be lowered without adding a medication to decrease inflammation (such as colchicine)

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[152] demonstrated that hyaluronic acid-modified verapamil-loaded CQDs, exhibited enhanced neuronal uptake and neuroprotective efficacy in an in vitro amyloid-induced neurotoxicity model, suggesting transporter-mediated BBB translocation and enhanced intracellular drug distribution [152]