Beta-catenin accumulates
References Advait Vasavada, Preeti Patel, Devang K
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When glutathione is available to help neutralize free radicals, NAD+ can be reserved for energy metabolism and cellular repair rather than stress management
Patients who are younger, female, and who have melanomas on their extremities generally have better prognoses.[4,8,9,11] The risk of relapse decreases substantially over time, although late relapses do occur.[12-15] Long-term follow-up is important for detection of recurrence, managing long-term effects, and surveillance of new lesions
Less NAD+ means slower healing and duller skin