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Propionate-induced gut hormone release is attenuated in FFA2 / primary murine L cells To evaluate the role of FFA2 in mediating propionate-induced PYY and GLP-1 secretion, we examined the effect of propionate on gut hormone secretion from primary colonic cultures from FFA2-deficient mice (FFA2 / )
CONCLUSION Oxidative stress occurs when the generation of reactive oxygen species (ROS) and other radical species overrides the scavenging capacity of antioxidants, either due to excessive ROS production or an inadequate availability of antioxidants
Rodent models, in particular, raise concerns due to their limited translational relevance to human physiology
At Baylor College of Medicine, Dr
6.3 Risk monitoring and safety considerations Safety remains a critical aspect of implementation
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