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Mechanistically, LONP1 ablation in cardiomyocytes promotes optic atrophy 1 (OPA1) processing (from L-OPA1 to S-OPA1) and dynamin-related protein 1 (Drp1) expression, while reducing mitofusin 1 (MFN1) expression, thereby enhancing mitochondrial fission

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If you experience discomfort, try taking with food or reducing to one dose per day

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