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These are summarised, together with the studies from which they were reported and the peptides measured, in electronic supplementary material (ESM) section Protein Selection and ESM Tables 1, 2

PMID: 19689277

Alpha Lipoic Acid (ALA) ALA is another powerful antioxidant that can cross into both water-soluble and fat-soluble parts of the cell

Curcumin analog ALZ003 can induce ubiquitination degradation of androgen receptor and significantly increase the sensitivity of GBM cells to temozolomide both in vitro and in vivo, and the mechanism may be related to ROS accumulation, lipid peroxidation and inhibition of GPX4, which are major features of ferroptosis

In honor of patient#1, the investigators named this novel ACOX1-mediated disease Mitchell Syndrome (distinct from Mitchell's disease, Erythromelalgia)

[16] [18] How should the injection be stored