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For clinical practice, several GLP-1 receptor agonists have been approved, such as (1) albiglutide, dulaglutide, liraglutide, and semaglutide (GLP-1 analogues) and (2) exenatide and lixisenatide (exendin 4 analogues)

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However, GLP-1 receptor agonists and dual GIP/GLP-1 receptor agonists represent different pharmacological classes with distinct safety profiles

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