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These compounds work by: Inhibiting thyroid-stimulating hormone (TSH) activity Blocking the binding of antibodies to TSH receptors Reducing the peripheral conversion of thyroxine (T4) to triiodothyronine (T3, the active form of thyroid hormone) Research has shown that bugleweed can effectively decrease thyroid hormone levels and alleviate symptoms associated with hyperthyroidism

While preclinical studies have value , they are not a one-to-one replica of what could actually happen if the drug is injected into a living human being

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