Extra caution is appropriate in patients with active cancer, recent cancer, unexplained masses, unexplained weight loss, pregnancy, breastfeeding, known allergy to peptide products, active infection, immune compromise, significant liver or kidney disease, active inflammatory or autoimmune disease flares, unusual clotting history, uncontrolled cardiovascular disease, use of chemotherapy or immune-modifying biologic therapy, and competitive athletes subject to anti-doping rules
Prescription weight loss drugs such as phentermine and topiramate (Qsymia) or bupropion and naltrexone (Contrave) are used for chronic, long-term weight loss, but only if adequate results occur
Unaddressed inflammation: GHK-Cu is anti-inflammatory, but it works upstream, not against active inflammatory conditions
That combination, more cells and longer-lived cells, is the basis for the interest in AHK-Cu as a hair regrowth ingredient
Gum disease is a common cause
In summary, after consideration of the public comment, we are finalizing our proposal without modification