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Residues in the anterior and posterior regions of TAD2 and the C-terminus of p53 TAD appear to be important for the interaction with FOXO4 FHD

Mol Nutr Food Res 60:21612175 Hattori Y, Okamoto Y, Maki T, Yamamoto Y, Oishi N, Yamahara K, Nagatsuka K, Takahashi R, Kalaria RN, Fukuyama H, Kinoshita M, Ihara M (2014) Silent information regulator 2 homolog 1 counters cerebral hypoperfusion injury by deacetylating endothelial nitric oxide synthase

Slightly nauseous, first week no significant weight loss, but 2nd & 3rd wk 3 lbs each

In this complex, both, the FOXO4-derived region and the cationic cell permeability peptide contribute to the interaction

doi: 10.1016/j.jaci.2004.06.007 252 GuizhouHCassanoPA

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