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Various small-molecule inhibitors targeting different stages of NLRP3 activation have been developed and investigated preclinically

"It had a section to which it belonged and therefore further exploration of those issues was not required." The World Anti-Doping Authority (WADA) issued a statement on April 22 this year, saying AOD-9604 was a substance still under pre-clinical and clinical development and has not been approved for therapeutic use by any government health authority in the world

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Cline MG, Burns KM, Coe JB, et al

launched Discover in 1985 as part of a financial-services strategy, but in 1993 spun it off as Dean Witter, Discover & Co