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MC1R activation by MT-1 drives cAMP-PKA signalling that upregulates nucleotide excision repair enzymes, reduces cyclobutane pyrimidine dimer formation following UV challenge, activates antioxidant defence pathways, and suppresses UV-induced inflammatory cytokine production through NF-B inhibition

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Dietary polyphenols promote growth of the gut bacterium Akkermansia muciniphila and attenuate high-fat diet-induced metabolic syndrome (in Eng)