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Materials and Methods Materials and Reagents TNBS, GSH, GSSG reductase, NADPH and diethylmaleate (DEM) were purchased from Sigma (Madrid, Spain)

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In the current review, we summarize the biological functions of mTOR, its regulatory effects on inflammation, and the curative effects of mTOR inhibitors in RA, thus providing references for the development of RA therapeutic targets and new drugs

Mechanism-based inhibitors of CD38: a mammalian cyclic ADP-ribose synthetase