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An FDA decision is anticipated by late 2026

Common injection sites used in trials include the abdomen, upper thigh, and upper arm

Common dosages Most protocols fall in this range: Low dose: 150-250 mcg per day Standard dose: 250-500 mcg per day Higher dose: 500-750 mcg per day Some people split the dose into two injections per day

B12 is needed for all brain and nervous system activity, energy production, formation of blood, cell metabolism, DNA synthesis, fatty acid synthesis, and homocysteine metabolism

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Schneider et al., 2016