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Therefore, to monitor the structural variations and quality of each docked receptor-ligand complex, RMSD and RMSF values for the ()alpha-carbon atoms of the protein were calculated in reference to the first pose of the MD simulation and analyzed by comparison to the respective values of the -carbon atoms in the apo-mh-Tyr structure (Figs

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Hexokinase 2 (HK2), the first rate-limiting enzyme of glycolysis, was recently identified as a critical target

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