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Rather than targeting hormones or appetite pathways, it works inside the cell itself blocking an enzyme called NNMT that sits at the centre of how fat cells manage energy

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Moreover, the long-term effects are often best realized when combined with other healthy lifestyle choices, such as a balanced diet and regular exercise

Pernicious anaemia, atrophic gastritis, proton pump inhibitors, metformin, and gastrointestinal surgery significantly impair B12 absorption

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