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If you have sensitive skin, you might want to patch test first, but its usually safe for most users.

Saxenda is a prescription-only medicine and must be prescribed and supervised by a qualified physician

Excessive Salt: Worsens fluid retention

Liraglutide was also associated with a reduction in mean ALT levels, which, however, disappeared after correction for changes in weight and HbA 1c (62, 63)

A 2024 review in Diabetes, Obesity & Metabolism , reported by Endocrine News (September 2025), found estimates ranging from 15% to 60% of total weight lost potentially coming from lean mass - a wide range that reflects genuine individual variation based on age, drug type, and lifestyle habits

Sawicka-Gutaj and colleagues, in International Journal of Obesity (April 2026), pooled 24 trials and concluded GLP-1 RAs deliver "quality" weight loss with relatively preserved lean tissue reductions of approximately 14% in lean body mass across treatment durations from 3 to 12 months