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Spatola, M

Anforth R, Carlos G, Clements A, Kefford R, Fernandez-Peas P

More GLP-1 was needed to have the same biological effect, meaning they were resistant to GLP-1." This switch around was so unexpected, the researchers ran further tests on mouse models with the PAM gene deactivated

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Introduction# GHRP-6 and Ipamorelin are both synthetic growth hormone secretagogues that stimulate pituitary GH release through the ghrelin receptor (GHS-R1a), but they sit at opposite ends of the selectivity spectrum

This selective physiological impact highlights the complexity of interpreting toxicity beyond survival endpoints