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Until then, the FDA reports that it will continue to retain enforcement discretion regarding pregnancy testing requirements

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Many patients taking this medication wonder whether they can safely extend fasting windows or practice intermittent fasting alongside their treatment

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In animal models, including db/db mice, streptozotocin (STZ)-induced diabetic models, and non-obese diabetic (NOD) mice, renal tissues show increased iron content, elevated levels of MDA and ACSL4 , and reduced GPX4 expression, which are the signature features of ferroptosis (Wang et al., 2020