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IGF-1 LR3 (Long R3 insulin-like growth factor-1) is an engineered analog of the naturally occurring peptide hormone IGF-1, redesigned in the laboratory so that it evades the binding proteins that normally sequester and regulate native IGF-1 in circulation

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Using a primary rat hepatocyte-based model, both aliphatic (e.g., sulforaphane, AITC) and aromatic (e.g., BITC, PEITC) isothiocyanates (at 20-40 M) have been found to downregulate CYP3A2 mRNA expression, as well as the activity of benzyloxyquinoline debenzylase, a marker of CYP3As (22)

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