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In plain terms, Lilly posits that selectively targeting AMY1 reduces food intake & body weight with less taste avoidance (aka food still tastes good!) with less GI side effects that seem to be driven by the non-selective activity of cagrilintide on all these receptors

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Lung cancer (LC) remains the leading cause of cancer-related mortality worldwide (1)

GLP-1 is a gut-derived hormone secreted in response to oral nutrient intake, exhibiting potent insulinotropic activity across several species, including humans [8]

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