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[DOI] [PubMed] [Google Scholar] 21.Sotiropoulos A, Ohanna M, Kedzia C, Menon RK, Kopchick JJ, Kelly PA, Pende M

Accessed November 13, 2024 [21] Shrivastava S, Sharma A, Saxena N, Bhamra R, Kumar S

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Research into these mechanisms is still evolving, and microdose-level effects have not been specifically studied in clinical trials, but the biological rationale is sound: activating two complementary hormonal pathways at low levels may produce a broader metabolic nudge than activating one pathway alone

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The Kyn/Trp ratio was also directionally higher in symptomatic patients than in asymptomatic V30M carriers, although this comparison did not reach statistical significance in the two-tailed analysis ( p = 0.0594)