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Phase 1 Trials In a first-in-human, randomized, placebo-controlled, single ascending dose, phase 1 trial in healthy participants, retatrutide demonstrated a favourable safety profile (similar to other incretin-based therapies) and early signs of efficacy with dose-dependent WL [42]
Taking the tablet at the same time each morning, on an empty stomach, and adhering strictly to the 30-minute waiting period before eating or drinking is essential for adequate absorption
Move Your Body (It Doesnt Have to Be Intense!) Regular movement helps increase GLP-1 and supports insulin sensitivity
Even if youre eating less overall, your meals should be nutrient dense
Patients should discuss eligibility and local availability with their GP or specialist diabetes/weight management service