Crosstalk between the immune system and neural pathways in interstitial cystitis/bladder pain syndrome
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doi: 10.3389/fphar.2026.1805808 Received 09 February 2026 Revised 26 March 2026 Accepted 26 March 2026 Published 01 May 2026 Volume 17 - 2026 Edited by Adolfo Andrade-Cetto, National Autonomous University of Mexico, Mexico Reviewed by Xiaolong Ji, Zhengzhou University of Light Industry, China Zeshan Ali, Bohai University, China Updates Copyright 2026 Xin, Zhang, Han, Liang, Kong, Guan, Sun, Liu, Han, Wang and Wang
The mechanism of action has been determined that KPV inhibits the activation of NF-kappaB and MAP kinase inflammatory signaling pathways, and reduces pro-inflammatory cytokine secretionacts via PepT1 expressed in immune and intestinal epithelial cells..[and] reduces the incidence of DSS- and TNBS-induced colitis indicated by a decrease in pro-inflammatory cytokine expression (Dalmasso et al., 2008)
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Regulation of skeletal muscle growth by the IGF1-Akt/PKB pathway: insights from genetic models
