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Many patients later restarted the original medication or switched to an alternative obesity treatment

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Medications such as semaglutide and liraglutide have been noted to provide benefits, including improved glycemic control, weight loss, and a reduction in cardiovascular risk

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In clinical trials, patients on semaglutide 2.4 mg lost an average of about 15% of their body weight over 68 weeks

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Retatrutide's longevity significance extends beyond weight loss: its effects on liver fat, glycemic control, and potentially cardiovascular and neurological outcomes position it as a multi-pathway intervention on metabolic aging

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