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The use of medications to help lose weight is suitable for adults based on their body mass index (BMI) and whether they have weight-related medical conditions

Eli Lillys orforglipron Phase III trial (ATTAIN-MAINTAIN) enabled injectable-to-oral transitions, preserving most weight loss over 52 weeks

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Kawashima I, Mitsumori T, Nozaki Y, Yamamoto T, Shobu-Sueki Y, Nakajima K et al

The trial included 80 people randomized to 0.1 mg of semaglutide, 78 to 0.2 mg, 82 to 0.4 mg, and 80 to placebo [3]

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