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Weekly dosing tends to boost adherence versus daily options

Tablets are counted

Although a basal level of radical production is important for proper physiological function [5], overexpression of radical species, either via increased production or decreased antioxidant defense, can result in oxidative damage to lipids, proteins, and nucleic acids, all of which may contribute to the pathophysiology of disease [6]

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128,132,133,134,135 This conservation allows for the establishment of animal models and preclinical studies for saRNA-based therapies

For one, it makes a robust clinical trial logistically tricky, said Christopher Milne, past director of research at the Tufts Center for the Study of Drug Development