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PubMed: (peer-reviewed) Babu M, et al

doi: 10.1038/s41586-021-04221-8 115 GeDGooljarSBKyriakouTCollinsLJSwaminathanRSniederHet al

Hyaluronic Acid: Acts as a delivery vehicle, pulling the peptide deep into the dermis

In an animal model of AD, mesenchymal stem cell (MSC)-derived exosomes delivered intranasally reduced extracellular plaque, inflammation, and glial activation

This results in a decrease in mitochondrial transcription factor TFAM and impaired mitochondrial function, which ultimately leads to increased vulnerability to oxidative stress and neuronal deterioration (Sharma A