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The PI3K/Akt pathway directly promotes glucose transporter translocation to cell membranes

investigated nutrient bypass of the foregut for its contributions to enhanced glucose tolerance, insulin sensitivity and incretin responses in humans after a mixed meal was delivered orally before RYGB (gastric), and both orally (jejunal) and by gastrostomy tube (gastric) postoperatively (Hansen et al., 2011)

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Montrose-Rafizadeh C, Avdonin P, Garant MJ, et al