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Repeat imaging every 23 years during long-term GLP-1 use can track any changes and inform preventive interventions such as weight loss moderation, resistance training, or supplementation

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These allosteric effects can be modulated through the action of carnitine acetyltransferase (CAT), a mitochondrial isoenzyme that transfers the acetyl groups from acetyl-CoA to carnitine, forming acetylcarnitine