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After 21 days, BW increased by 2.6% 0.71% in V rats and was reduced in the other cohorts by 8.7% 0.91% (CS), 5.6% 0.50% (PF) or 9.0% 0.42% (WM) (all P 3 C)

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Across tendon, muscle, and connective-tissue models, it promotes regenerative healing rather than scar formationimproving strength, vascularization, and recovery even under impaired conditions

Neuronal transporters regulate glutamate clearance, NMDA receptor activation, and synaptic plasticity in the hippocampus

10.1042/BST20200270 Summary Keywords GLP-1, immunemetabolic signaling, metabolic disease, neuroendocrine peptides, orphan receptors, peptide therapeutics, polypharmacology Citation Niazi SK (2026) Beyond GLP-1: underexplored peptidereceptor systems as the next frontier in drug discovery