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This accumulation contributes to PD by suppressing the activity of peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1), a transcriptional coactivator involved in regulating mitochondrial biogenesis and oxidative metabolism (Shin et al

Targeting ferroptosis alleviates methionine-choline deficient (MCD)-diet induced NASH by suppressing liver lipotoxicity

doi:10.1016/j.jneuroim.2022.577915

We speculate that this apparent contradiction may stem from differences in the subtype selectivity and effective concentrations of HDAC inhibitors

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