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Gastrointestinal side effects are the most common early experiences, affecting 3050% of patients to varying degrees

Causality is not proven, but chronic daily use should be minimized

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In naturally aged mice, the renal function improvements were statistically significant but more modest a pattern consistent with the lower but still meaningful senescent cell burden in normal aging

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These drugs not only affect eating behavior but can also have an impact on emotional behavior and cognitive function due to the presence of receptors for these neurochemical systems in specific areas of the brain