Anti-inflammatory activity is the earliest response, with cytokine suppression and nitric oxide modulation reducing swelling from 24 to 72 hours in acute injury models
Ehrmann DA, Liljenquist DR, Kasza K, Azziz R, Legro RS, Ghazzi MN et al (2006) Prevalence and predictors of the metabolic syndrome in women with polycystic ovary syndrome
Also, additional environmental factors such as pollutants may also affect its level
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Notably, a cross-sectional study conducted in an area with poor soil Se showed that Se levels in patients in GD with or without GO were lower than in normal healthy controls (27), which would seem to be able to suggest that relatively low Se level is an independent risk factor for GD