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After 12-18 hours centrilobular hepatic necrosis occurs which may be accompanied by renal tubular necrosis and hypoglycaemia that may progress to coma

Reactive oxygen species (ROS) such as hydrogen peroxide and alkylperoxides produced by various metabolic processes can cause irreversible oxidative damage to the cell if they are not rapidly detoxified by antioxidant defenses

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Our previous studies in T1D [26] and CD [18] cohorts have mainly focused on the associations of PFAS exposure with the disease risk

Meanwhile, we have to evaluate the impact of ferroptosis on the immune system in both the short and long term