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Researchers comparing semaglutide withdrawal symptoms should note that discontinuing GLP-1 or GIP/GLP-1 agonists can lead to rebound appetite and weight regain if not managed carefully

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Additionally, preliminary studies are indicating that the risk of major depressive disorder in a patient with a MTHFR mutation is even greater when coupled with other environmental factors such as trauma, diet, and stress

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L.NiuZ.PessiJ.KazakouM.RaptisK.McCabeR.et al (2025)

Clin Med 20(2):124 Hughes C, Nichols T, Pike M, Subbe C, Elghenzai S (2020) Cerebral venous sinus thrombosis as a presentation of COVID-19