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As for the captive zebras, the non-parametric MannWhitney U test was used because of the low and unbalanced sample size

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DOI: 10.3390/nu17091410

5 A recent cohort study of NAD+ and a proprietary combination of B vitamins, amino acids, and DL-phenylalanine (an enkephalinase inhibitor) IV for substance abuse disorder found statistically significant improvement in cravings, anxiety, and depression scores for patients on IV NAD+.5 Another study on patients with alcohol or opiate addiction found doses of 500-1500mg per day (in combination with some vitamins, amino acids, and n-acetylcysteine) for 10 days to reduce cravings and number of relapses when patients were surveyed 12-20 months post treatment

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