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The same gastrointestinal side effects, central adaptations, and pleiotropic actions that once discouraged development are now recognized as manageable features of peptide pharmacology when appropriately contextualized

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showed that exenatide therapy for that 3-mo in patients with obesity and pre-diabetes had similar effects on microvascular endothelial function, markers of inflammation, oxidative stress, and vascular activation, as metformin

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Lira was found in PA-induced Kupffer cells to reduce HF diet-induced hepatic steatosis by inhibiting NOD-like receptor thermal protein domain associated protein 3 (NLRP3) inflammasome activation [62]

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While GLP-1s have been largely studied and used for T2D, their benefits in T1D have not been explored as extensively

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Cardiovascular advantages include lowered blood pressure, enhanced lipid profiles, and less arterial stiffness (Sheahan et al

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