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We pooled the studies using random-effects model [7] in the presence of statistical or other heterogeneity, and fixed-effects models otherwise [8]

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Medical Uses : Methylene blue has various medical uses, primarily as a dye and a therapeutic agent such as preventing ifosfamide-induced encephalopathy (a potentially fatal toxicity of ifosfamide, a cancer drug) in cancer patients, and preventing urinary tract infections

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