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After integrating these datasets, the overall PBMC landscape remained stable: 11 major immune cell groups were identified using similar clustering structure and canonical marker gene expression (Supplementary Fig

SW, JW, DG, TM, PT, and SC contributed to data collection and data processing

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Acknowledgements Portions of the MS-based proteomics work described herein were performed at the Environmental Molecular Sciences Laboratory (grid.436923.9), a US Department of Energy (DOE) National Scientific User Facility located at the Pacific Northwest National Laboratory (PNNL)

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