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Data availability All data generated or analyzed during this study are included in this published article (and its Supplementary Information files)

Frequently Asked Questions Is it safe to take creatine while on Wegovy or semaglutide

Key considerations for concurrent use: Both medications can be prescribed together when clinically indicated Thyroid function should be monitored when starting or changing Saxenda doses TSH (and possibly free T4) should be checked 6-8 weeks after starting or titrating Saxenda Significant weight loss may alter levothyroxine requirements in some patients Thyroid function should be reassessed after substantial weight changes It is essential that prescribing decisions are made by qualified healthcare professionals who can assess individual patient circumstances, including thyroid status, cardiovascular health, and weight management goals

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Interim Policy on Compounding Using Bulk Drug Substances Under Section 503A of the FD&C Act (Guidance Document PDF) FDA