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Therapeutic Potential of CKD-506, a Novel Selective Histone Deacetylase 6 Inhibitor, in a Murine Model of Rheumatoid Arthritis

Lower GLP-1 means increased hunger and weight regain

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Of course, more receptors also mean careful management dosing has to be titrated to minimize side effects, and well learn from ongoing trials if certain patient groups respond better than others