Our study is the first to demonstrate that ESCs in the process of ferroptosis, stimulate VEGFA and IL8 secretion, which may contribute to endometriotic lesion angiogenesis
Therefore, to bridge the gap between mechanistic studies and clinical application, stratified randomized controlled trials that employ rigorously characterized microbial strains, standardized dosing protocols, and prespecified, patient-centered primary endpoints must be prioritized in future research
This aligns with research: modest effect, mild side-effects, require lifestyle support and good monitoring
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For instance, vascular risk factors, such as hypertension and reduced low-density lipoprotein (LDL) levels, result in disruption of the BBB structure, which accelerates the accumulation of A deposition and tau pathology [77]