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however, the application is limited by indications and usually needs to be combined with lifestyle interventions to reduce the risk of weight rebound

AI analysis of Reddit posts uncovered potential side effects of GLP-1 drugs that may be underreported, demonstrating the value of social media in early drug safety insights

Cai X, et al

The most common side effects were mild to moderate and mostly affected the stomach and intestines

doi: 10.1016/S0140-6736(08)61206-4

To accomplish this feat, the enzyme can be split into two parts, and with a properly chosen splitting site, the enzyme could be reconstituted and recover its catalytic activity when these two parts are brought together, which can be achieved by the above-mentioned dimerization systems