Weight Loss Efficacy: Head-to-Head Trial Data Retatrutide produced the highest average weight loss in its Phase 2 trial, but the two drugs were tested in separate studies at different time points, so the comparison is indirect rather than a direct trial
In a Phase 2 clinical trial published in The Lancet, the drug significantly improved blood-sugar control and reduced body weight in people with Type 2 diabetes compared with a placebo
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These developments underscore the expanding arsenal of diabetes drugs available to clinicians
Among the 12% of adults who have ever taken GLP-1 drugs, most report taking them, at least in part, to treat a chronic condition like diabetes or heart disease, with fewer saying they took them only to lose weight