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The half-life of DSIP depends on its environment: In vitro, it exhibits low molecular stability due to the action of specific aminopeptidase enzymes, with a half-life of only 15 minutes

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The Jackson Laboratory-USA) mice were subcutaneously inoculated with human primary WM115 (4 10 6 ) and metastatic MRA6 melanoma cells (2 10 6 ) in 100 L PBS into the shaved flank

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